A Climate Responsive Active with Biological Intelligence
As global temperatures reach record highs, skin faces unprecedented environmental fatigue and thermal shocks. MANJAR is Assessa's groundbreaking solution: a climate-adaptive active that teaches the skin to defend itself and maintain hydration exactly when needed most. Unlike conventional moisturizers that merely deposit a superficial barrier, MANJAR stimulates the skin's internal 'irrigation system', transforming passive surface care into permanent biological resilience.
Filaggrin Boost Under Extreme Thermal Stress
Aquaporin-3 Expression Increase
Natural Origin Index (ISO 16128)
The world is witnessing record-breaking temperatures and drastic shifts in humidity. The UN describes this era as “Climate Collapse,” in which the skin is subjected to constant environmental fatigue. This stress creates a “Thermal Shock” that destabilizes the skin through environmental fatigue, barrier vulnerability, and structural collapse.
MANJAR is a bio-adaptive active ingredient designed to rebuild the skin’s structural architecture.
It is a masterpiece of Green Chemistry combining upcycled Green Coconut Jelly (Endocarp), rich in polysaccharides and amino acids, with Hydrolyzed Plum Pulp, densely packed with uronic acids, polyphenols, and fruit acids.
Instead of relying on synthetic films, MANJAR targets the two essential biological pillars of cellular hydration:
Filaggrin & NMF Boost: Stimulates Filaggrin, the key precursor protein for Natural Moisturizing Factors, strengthening epidermal cohesion.
Aquaporin-3 Channeling: Boosts Aquaporin-3 expression, which transports water and glycerol between cells to optimize the skin's internal water flow.
While standard moisturizers only create a surface barrier, MANJAR stimulates Aquaporin-3 channels and Filaggrin production, recharging the skin's endogenous water reservoirs.
Clinically proven under real thermal and humidity stress (fluctuations from 42ºC to 0ºC), MANJAR teaches the skin to defend itself and maintain hydration in extreme weather.
Preclinical trials on human skin explants under extreme temperature stress demonstrated a 144.8% increase in Filaggrin expression over controls (and +61.3% vs Placebo).
In vitro RT-qPCR molecular gene expression tests confirmed a 26.8% increase in Aquaporin-3 expression, ensuring active glycerol and water transport across epidermal layers.
Crafted from coconut pulp recovered from coconut water processing and plum pulp, transforming agricultural co-products into a high-value bioactive ingredient.
Produced using ASSESSA's exclusive bio-extraction process without harsh synthetic solvents or petroleum derivatives, meeting global ESG standards.
Hydration and skin barrier markers in Human Epidermal Keratinocytes
Molecular Gene Expression (RT-qPCR)
MANJAR was tested in human keratinocytes over 48 hours, confirming a significant increase in the expression of Aquaporin-3 and Filaggrin.
MANJAR increases Aquaporin-3 expression by 26.8%, enhancing the skin’s internal water transport system.
MANJAR increases Filaggrin expression by 52.2%, strengthening epidermal cohesion and NMF production.
Performance Validated Under Extreme Stress (40°C)
To evaluate the efficacy of SERUM SKIN MANJAR (3%) against environmental fatigue and chronic dehydration, human skin explants were exposed to extreme temperature fluctuations (42 ºC to 0 ºC) at low humidity (30 ± 5%) to simulate extreme thermal stress.
Treatment with Serum MANJAR 3% resulted in a 144.8% increase in Filaggrin compared with the Control group, and a 61.3% increase compared to Placebo.
Environmental stress triggered a significant 65.8% increase in Aquaporin-3 expression. Treatment with Serum MANJAR 3% maintained these elevated levels, optimizing water transport under stress.
MANJAR's primary raw material — the nutrient-dense green coconut gelatinous pulp — is recovered through an advanced upcycling process from the coconut water industry. What was once discarded as industrial waste is transformed into a high-performance, bioactive material, significantly reducing environmental impact.
Unlike many industry-standard humectants obtained through chemical processing and synthetic solvents, MANJAR is produced using ASSESSA’s exclusive bio-extraction process, which preserves the full integrity of phytonutrients as found in nature and guarantees a 99.55% Natural Origin Index.
Discover how MANJAR activates the skin's internal irrigation system and teaches cellular defense against climate change, heat peaks, and extreme thermal shock.
"MANJAR is a biological 'insurance policy' for the skin in an ever-changing world."